Adrenomedullin surges are linked to acute episodes of the systemic capillary leak syndrome (Clarkson disease).
Author | |
---|---|
Abstract |
:
Systemic Capillary Leak Syndrome (SCLS) is an extremely rare and life-threatening vascular disorder of unknown etiology. SCLS is characterized by abrupt and transient episodes of hypotensive shock and edema due to plasma leakage into peripheral tissues. The disorder has garnered attention recently because its initial presentation resembles more common vascular disorders including systemic anaphylaxis, sepsis, and acute infections with the Ebola/Marburg family of filoviruses. Although approximately 70-85% of patients with SCLS have a concurrent monoclonal gammopathy of unknown significance (MGUS), any contribution of the paraprotein to acute flares is unknown. |
Year of Publication |
:
2018
|
Journal |
:
Journal of leukocyte biology
|
Date Published |
:
2018
|
ISSN Number |
:
0741-5400
|
URL |
:
http://www.jleukbio.org/cgi/pmidlookup?view=long&pmid=29360169
|
DOI |
:
10.1002/JLB.5A0817-324R
|
Short Title |
:
J Leukoc Biol
|
Download citation |