MHC class II gene silencing in trophoblast cells is caused by inhibition of CIITA expression.
| Author | |
|---|---|
| Abstract |
:
Major histocompatibility complex (MHC) class II molecule expression is specifically suppressed on fetal trophoblasts, even in response to interferon (IFN)-gamma, a potent inducer of MHC class II genes. The suppression of class II induction has been suggested to play a role in preventing rejection of the fetal allograft. The mechanism of this suppression is unknown. |
| Year of Publication |
:
1998
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| Journal |
:
American journal of reproductive immunology (New York, N.Y. : 1989)
|
| Volume |
:
40
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| Issue |
:
6
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| Number of Pages |
:
385-94
|
| ISSN Number |
:
1046-7408
|
| URL |
:
https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1046-7408&date=1998&volume=40&issue=6&spage=385
|
| DOI |
:
10.1111/j.1600-0897.1998.tb00423.x
|
| Short Title |
:
Am J Reprod Immunol
|
| Download citation |
