A new type of DNA "light-switch": a dual photochemical sensor and metalating agent for duplex and G-quadruplex DNA.
| Author | |
|---|---|
| Abstract |
:
Ru(bpy)2dppz, a well studied "light-switch" metal complex, transforms into a photochemical "light-switch" and DNA damaging agent by incorporating structural strain. This distorted compound is photoreactive and ejects a ligand upon binding duplex and G-quadruplex DNA, producing a reactive metal center that metalates the DNA. |
| Year of Publication |
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2014
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| Journal |
:
Chemical communications (Cambridge, England)
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| Volume |
:
50
|
| Issue |
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3
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| Number of Pages |
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311-3
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| Date Published |
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2014
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| ISSN Number |
:
1359-7345
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| URL |
:
https://doi.org/10.1039/c3cc47269h
|
| DOI |
:
10.1039/c3cc47269h
|
| Short Title |
:
Chem Commun (Camb)
|
| Download citation |
